EFFECTIVENESS OF EARLY CARE TUTORING ON QUALITY OF LIFE, LIFESTYLE BEHAVIORS AND BIO PHYSIOLOGICAL OUTCOME AMONG OBESE ADOLESCENTS AND KNOWLEDGE ON OBESITY MANAGEMENT AMONG MOTHERS AT SELECTED SCHOOLS IN CHENNAI.

Background: The rising prevalence of adolescent obesity is associated with an increase in co-morbidities and Up to 4 three-fourth of children with overweight/obesity remain so in adulthood. . Objectives: 1.To assess and compare the level of Quality Of Life, Life Style Behaviors and Biophysiological Outcome among obese adolescents between experimental and control group. 2. To assess and compare the level of knowledge among obese adolescent's mothers between experimental and control group. 3. To assess the Effectiveness of Early Care Tutoring on Quality Of Life, Life Style Behaviors and Biophysiological Outcome among obese adolescents between experimental and control group. 4. To assess the Effectiveness of Early Care Tutoring on the level of knowledge among obese adolescent's mothers between experimental and control group. 5. To correlate the Mean differed score of Quality Of Life, Life Style Behaviors and Biophysiological Outcome among obese adolescents in experimental and control group. Methodology: A quasi experimental research design was adopted. After screening a total 20 elderly people, 10 for each experimental and control group were selected were selected by using non probability purposive sampling technique in a selected Schools. The pre test data was collected through the structured and modified tools for Quality of Life (QOL), Lifestyle behavoirs and Biophysiological out comes was given for a period of 4 weeks and post test was conducted. Collected data were analyzed by using descriptive and inferential statistics. Majority of the Results: adolsecents aged 14,female, first child of the family. Socioeconomical staus was upper class. All of them were residing in urban . distance from school was <1kn and using either bi-cycle or bike.The present study showed that there was an improvement between pre test and post test 2 and 3 in QOL and Lifestyle behaviors. Only BMI showed significance in post test 2 and 3, other anthropometrics were not significant. There was a correlation between QOL and LSB & QOL and BMI. Early care tutoring packages had a strong impact on adolescents' QOL, LSB and Biophysiologicaloutcomes. The overall statistically significant difference Conclusion: in the level Early Care Tutoring was effective and found to be significant in modifying the Quality of Life, Life style Behavior and biophysiological outcome among Obese Adolescents

Assess the Depression and Quality of Life among Women Suffering from Selected Gynaecological Cancers Attending Oncology Units of Selected Hospitals

Backgrounds: Gynecological cancers are significant and probable life-threatening diseases that harm patients' physical and psychological health. The leading cause of death in female抯 psychological problems like depression endure and can cause an extra burden during their treatment. Therefore, this study helps evaluate depression and well-being among gynaecological malignancies. Methods: Women's depression was evaluated by a standardized CES-D Scale and QOL by WHOQOL Bref scale, a sample of 100 women with cancers admitted at HSK and Kerudi cancer hospital, Bagalkot was selected using a purposive sampling technique, descriptive survey design was adopted. Statistical data were tested and scrutinized using descriptive and inferential analysis. Results: 100% of women had moderate depression. The mean percentage of depression score was 61.45% with mean and SD (37�9). Of the women, 71 % had moderate, 21%had poor, and 8% had good QOL. The mean percentage of QOL of women was 48.1% with mean and SD (62.5�.1). A Strong relation was found between depression scores with your family members known to you (?=4.52, p<0.05), Area of residence (?=3.88, p<0.05), and whether you have undergone previously any surgery for the treatment of cancer (?=8.93, p<0.05). No association was found between QOL scores with study variables. A Negative correlation (r=-0.27, p<.05) was found between depression and Total QOL scores. Conclusion: Most patients have moderate depression and moderate QOL. This study is effective in identifying depression and QOL

Impact of color vision deficiency on the quality of life in a sample of Indian population: Application of the CVD-QoL tool

Purpose: To investigate the quality of life (QoL) in a sample of color vision deficit (CVD) patients in India and how color vision deficiency affects them psychologically, economically, and in productivity related to their work and occupation. Methods: A descriptive and case–control study design using a questionnaire was conducted on N = 120 participants, of whom 60 were patients of CVD (52 male and eight female) who visited two eye facilities in Hyderabad between 2020 and 2021 and 60 were age?matched normal color vision participants who served as controls. We validated English–Telugu adapted version of CVD?QoL, developed by Barry et al. in 2017 (CB?QoL). The CVD?QoL consists of 27 Likert?scale items with factors (lifestyle, emotions, and work). Color vision was assessed using the Ishihara and Cambridge Mollen color vision tests. A six?point Likert scale was used, with lower scores indicating poor QoL (from 1 = severe issue to 6 = no problem). Results: The CVD?QoL questionnaire’s reliability and internal consistency were measured, including Cronbach’s ? (? =0.70–0.90). There was no significance between the group in age (t = ?1.2, P = 0.67) whereas the Ishihara colour vision test, scores showed a significant difference (t = 4.50, P < 0.001). The QoL scores showed a significant difference towards lifestyle, emotions and work (P = 0.001). The CVD group had a poorer QoL score than the normal color vision group odds ratio [OR] =0.31, 95% confidence interval [CI], (P = 0.002, CI = 0.14–0.65, Z = 3.0) . In this analysis, a low CI indicated that the OR was more precise. Conclusion: Color vision deficiency affects Indians’ QoL, according to this study. The mean scores of lifestyle, emotions, and work were lower than the UK sample. Since CVD is underreported and possibly affects developing countries more, advocacy for a new health care plan on CVD is essential. Increasing public understanding and awareness could also help diagnosing the CVD population

Clinical Profile and Quality of Life of Incident Hemodialysis Patients

Hemodialysis is the most commonly used treatment modality for end stage renal disease. A 6 months observational study was conducted in the Dialysis unit of Kasturba Hospital, Manipal to study the clinical profile, quality of life with the help of KDQoL SF 36 questionnaire and factors affecting quality of life of hemodialysis patients. A total of 45 participants were included who initiated dialysis in the year 2018 and 2019 and were receiving dialysis in our hospital. Out of 45 participant 77.8% were males and 22.2% were females, the mean age was 55.29 (11.29) years. 23 patient-initiated dialysis in the year 2018 22 patients-initiated dialysis in the year 2019. The prevalence of hypertension, diabetes mellitus and cardiovascular diseases in this population were found to be 95.2%, 35.6% and 8.9% respectively. The mean scores of the sub scales were analyzed with the help of scoring manual and descriptive statistics. In the result it was found the hemoglobin, intradialytic weight gain were found to be positively correlated with the Physical component summary (PCS) and Mental component summary (MCS). Effects of kidney disease was found to be very strongly and positively correlated with dialysis vintage. In the result of the study due to its smaller population we cannot determine more factors which were affecting the Quality of life scores.

Quality of Life of Chronic Kidney Disease Patients on haemodialysis in a tertiary care centre

Background: End-stage renal failure is a chronic disease that greatly impacts a pa?ent’s health-related quality of life mainly due to the imposed limita?ons in almost all domains of their daily lives affec?ng >10% of the general popula?on worldwide, amoun?ng to >800 million individuals. Haemodialysis consists of a complex procedure for pa?ents that requires frequent hospital or dialysis centre visits, three ?mes a week, Objec?ves: To assess Quality of life and to find an associa?on between QOL, socio-demographic factors, and clinical variables among chronic kidney disease pa?ents on haemodialysis Material and methods: The sample consisted of 89 pa?ents undergoing haemodialysis. Data was collected by a specially designed ques?onnaire (KDQOL-36) which apart from the socio-demographic and clinical variables, also included the kidney disease variables for assessing the quality of life. Results: The results indicated that haemodialysis pa?ents’ QOL was impacted by socio-demographic and clinical factors related to dialysis. The study majorly reported that these factors played a major role directly and indirectly, with social ac?vi?es affec?ng more followed by emo?onal disturbances and physical ac?vi?es. Conclusion: QOL of haemodialysis pa?ents can be improved by correctable factors like anemia, diabetes, and hypertension. Healthcare prac??oners can create personalised interven?ons that are tailored to the needs of haemodialysis pa?ents by having a deeper grasp of the variables like treatment of co-morbidi?es decrease in the number of hospitaliza?ons, be?er management of anemia and decreasing the distance between home & dialysis center.

Impact of COVID-19 on quality of life in Peruvian older adults: construct validity, reliability and invariance of the COV19-Impact on Quality of Life (COV19-QoL) measurement

Abstract The aim of the present study was to translate into Spanish and evaluate the psychometric evidence of the Impact on Quality of Life (COV19-QoL) applied to a sample of Peruvian older adults ( N = 298; 58.1% women, 41.9% men, mean age 65.34 years [SD = 11.33]). The study used techniques from the Classical Test Theory (CTT) and Item Response Theory (IRT). The findings confirmed the single factor structure of the COV19-QoL, high internal consistency reliability, measurement invariance by gender, and all items demonstrated adequate discrimination and difficulty indices. In this sense, the items allow adequate discrimination between low, medium and high levels of the impact of the COVID-19 pandemic on quality of life. In addition, a greater perceived impact of the pandemic on quality of life is necessary to answer the higher response options of the COV19-QoL. In conclusion, the COV19-QoL is a valid measurement scale of the impact of the COVID-19 pandemic on the quality of life of Peruvian older adults.

Establishment and internal validation of a risk prediction model for urinary incontinence after transurethral holmium laser enucleation of the prostate / 现代泌尿外科杂志

【Objective】 To establish a model for predicting the risk of urinary incontinence after holmium laser enucleation of the prostate (HoLEP). 【Methods】 The clinical data of 258 patients with benign prostatic hyperplasia (BPH) who underwent HoLEP in our hospital during Jan.2019 and Feb.2022 were retrospectively analyzed. According to the occurrence of urinary incontinence after surgery, they were divided into the urinary incontinence group (n=84) and non-urinary incontinence group (n=174). Lasso regression was used to screen the predictors of urinary incontinence after HoLEP. Logistic regression was used to establish a suitable model, and a nomogram of urinary incontinence after HoLEP was drawn. Bootstrap was used to verify and draw the calibration curve of the model, calculate the C index, and draw the clinical decision curve to further verify the accuracy and identification ability of the model. 【Results】 Predictors including International Prostate Symptom Score (IPSS), Quality of Life Score (QoL), body mass index (BMI), diabetes, prostate volume (PV), and prostate-specific antigen (PSA) were selected, based on which a prediction model was constructed. The area under the receiver operating characteristic (ROC) curve of the prediction model was 0.766 0, and the 95% confidence interval was 0.704-0.828. Bootstrap internal validation showed a C-index of 0.766 2, and the calibration model curve coincided well with the actual model curve. The clinical decision curve analysis showed that the model had high accuracy, and net benefit in the probability of urinary incontinence was within 10% to 82%. 【Conclusion】 IPSS, QoL, diabetes, prostate volume, and PSA are predictors that can affect the occurrence of urinary incontinence after HoLEP. The model has high accuracy, identification ability and net benefit.

Quality of life among geriatric population: A cross-sectional study to assess the quality of life among geriatric population covered under urban health training center of a tertiary care hospital in Kancheepuram, Tamilnadu

Introduction: To assess the quality of life among geriatric population covered under urban health training center of a tertiary care hospital in Kancheepuram and to find out if there are any associated factors affecting them. Methods: This cross-sectional study was conducted at Saveetha Medical College, Chennai, India. It comprised geriatric population of males and females aged above 60 and 58 respectively. A pre tested semi structured questionnaire was used for collecting socio demographic data, whereas a WHO standard questionnaire was used to assess the QOL. Analysis was done using SPSS software. Objectives: To assess the quality of life among the geriatric age group and to assess the factors affecting the quality of life among the geriatric population. Results: Out of the 228 geriatrics interviewed, females (68.66) were found to have a better QOL when compared to males (67.85). The p values obtained from the chi square tests were found to be significant for age (0.056), marital status (0.004), family type (0.002), co morbid factors (0.001), alcoholics (0.00). Conclusion: From the study we could infer that co morbidity, marital status, type of family have a significant association with QOL.

Quality of Life in Patients with Leprosy using WHOQoL-Bref Questionnaire: A Pilot Study

Quality of life (QoL) is a subjective measure which includes physical, psychological and social health and its relationship with the environment. Leprosy results in progressive damage to peripheral nerves in untreated or inadequately treated patients leading to nerve impairment and visible disabilities which may affect the quality of life. A descriptive cross-sectional study was conducted in a tertiary care centre among patients with leprosy over a period of six months, and quality of life status was evaluated using the WHOQoL Bref questionnaire based on four domains, namely physical, psychological, social and environmental. A total of 50 patients (males: females - 36:14) in the age group of 19-69 years were evaluated. Most patients (64%) belonged to the borderline tuberculoid spectrum. Patients with a disability accounted for 16% (8 out of 50) of the total cases. The psychological domain was the most commonly affected domain among patients. Females had lower scores than males in all domains. Elderly patients, patients with lepromatous leprosy and those with facial involvement had lower scores. Domain outcomes in lepra reactions were lower than in other types of leprosy. The study observed that leprosy in the ageing population, women and patients with severe forms of leprosy, associated with disabilities, have poorer quality of life.

Psychological Effect Of Chemosensory Deficits In COVID-19 Patients

Background:Mental health was broke greatly in this COVID-19 pandemic. Objective: This study aimed to detect the effect of chemosensory deficits from deadly pandemic COVID-19 on mental health. Material And Methods:A survey questionnaire was used to detect the level of psychological problems in this cross-sectional observational study in sample size of 200 COVID-19 positive patients.Result:The findings shows that there is increase in prevalence of psychological problems which affects mental health drastically like isolation, anxious, afraid of failure to recover back which hampering their quality of life.Conclusion:This study emphasizes on the importance and prevention of psychological problems as well as role of counselling & treatment.

Quality of life and its predicting factors for Tunisian children with cerebral palsy

Background: Cerebral palsy (CP) can cause motor, sensory, perceptual, cognitive, communication and behavioural disorders. The complexity of this condition justifies measuring the quality of life (QOL) of children with CP. This measurement depends on personal and socio-economic factors, hence the relevance of performing it in our cultural context of Tunisia. Objectives: The objectives of this study were to assess the QOL of Tunisian children with CP and to identify predictive factors for QOL. Method: A cross-sectional study using a self-administered questionnaire (the CP QOL-Child) was employed. It included 68 children with CP and their parents who consulted the outpatient clinics of Physical Medicine and Rehabilitation of the University Hospital of Sahloul Sousse. Results: The QOL of children with CP was altered, and the mean total score for the CP QOL-Child was 59.3 (± 14). All domains were affected by this alteration. Six predictive factors for lowered QOL in children with CP were identified, namely age older than 6 years, swallowing disorders, more intense chronic pain, greater level of motor impairment, the use of botulinum toxin injection and the absence of verbal communication. Conclusion: Intervention with children with CP must be mindful of their altered QOL. Five out of the six predictive factors of QOL are modifiable through a multidisciplinary approach within the framework of the International Classification of Functioning, Disability and Health (ICF). Contribution: The multiplicity of the factors associated with QOL revealed by this study incites clinicians to adopt the ICF approach by displaying its practical implications on the efficiency of the medical intervention.

Translation and validation of the Filipino version of the University of Washington Quality of Life Questionnaire (UW-QOL) for patients with head and neck cancer

Objective@#To translate the University of Washington Quality of Life (UW-QOL) questionnaire into Filipino and to validate it among a sample of patients with head and neck cancer. @*Methods@#Design: Cross-sectional study. Setting: Tertiary Government Training Hospital. Participants: 33 patients.@*Results@#A total of 33 patients were recruited in this study. Eighteen (54.5%) were male, and 15 (45.5%) were female aged 24-79 years old (mean age 52.85 ± 11.81 years old) completed the study. All items in the Filipino translation of the UW-QOL had a content validity index. The raters in face validation had 100% agreement in almost all items except for the appropriateness of font size and space of the questionnaire. The Cronbach’s alpha of the Filipino version of the questionnaire was 0.8596. The alpha score when each of the items was deleted remained within the range of 0.83 – 0.86. The intraclass correlation coefficients of all items were greater than 0.9. For all items, there were no significant difference observed between the test and retest scores. @*Conclusion@#This study showed that the Filipino translation of the UW-QOL is culturally adapted, internally consistent and stable. It is as reliable as the original English version in assessing health related QOL, and valid for assessing HR-QOL among patients with head and neck cancers.

Impacto en la calidad de vida por la comprensión del tinnitus / The Quality of Life impaction by Tinnitus Comprehension

El tinnitus es la sensación de sonido en ausencia de cualquier fuente externa. Nuestro objetivo fue evaluar la repercusión del tinnitus en la calidad de vida. Se inscribieron 25 pacientes con tinnitus con una amplia gama de umbrales de pérdida auditiva (HLT) y estado de gravedad de tinnitus. La gravedad, la ansiedad y la depresión del tinnitus se evaluaron mediante el inventario de discapacidades por tinnitus (THI), el índice funcional de tinnitus (TFI) y la escala de ansiedad y depresión hospitalaria (HADS), respectivamente. Se realizó una audiometría de conducción aérea de tono puro. El impacto de la percepción del tinnitus en la calidad de vida se encontró más alto en el grupo de sufrimiento. La escala de ansiedad y depresión figuraba en 40% y 60%, respectivamente. El uso de la mano fue de 20 diestros y 5 zurdos. El tinnitus bilateral se está experimentando en el 76%. El LH se presentó en 17 (68%) de los pacientes con tinnitus. La descripción del sonido del tinnitus como silbido (40%), siseo (24%), pulsante (16%), timbre (8%) y ruidos de tono alto (12%). Con respecto al cuestionario THI, los sujetos con tinnitus se dividen en 60% (leve), 30% (moderado) y 10% (grave). Mientras que el cuestionario TFI, el 50% mostró un (leve), el 25% (moderado) y el 25% mostró (severo). Postulamos una fuerte asociación positiva significativa entre HADS y la gravedad del tinnitus: THI (P = 0,000) y TFI (P = 0,001). Esos datos revelaron que la percepción del tinnitus tiene impactos negativos en la calidad de vida mientras que la gravedad puede verse alterada por la lateralidad

Tinnitus is the sensation of sound in the absence of any external source, and the aim is to assess the impaction of tinnitus on QoL. 25-tinnitus sufferers were enrolled with a wide range of hearing loss thresholds (HLT) and tinnitus severity status. Tinnitus severity, anxiety and depression were assessed using tinnitus handicap inventory (THI), tinnitus functional index (TFI), and the hospital anxiety and depression scale (HADS), respectively. Pure tone air conduction audiometry was performed. The impaction of tinnitus perception on QoL was found higher in suffering group. The anxiety and depression scale figured in 40%, and 60%, respectively. The handed use was 20 rights handed and 5 left-handed. Bilateral tinnitus is experiencing in 76%. The HL occurred in 17(68%) of tinnitus patients. The description of tinnitus sound as whistling (40%), hissing (24%), pulsating (16%), ringing (8%), and high pitch noises (12%). Regarding THI questionnaire, tinnitus subjects are divided to 60% (mild), 30% (moderate), and 10% (severe). While TFI questionnaire, 50% showed a (mild), 25% (moderate), and 25% showed (severe). We postulated a strong significant positive association between HADS and tinnitus severity: THI (P=0.000) and TFI (P= 0.001). Those data revealed that tinnitus perception has negative impacts on QoL, and the severity may be altered by laterality.

Active aging health determinants among working and retired Filipino older persons living in an urban academic campus

OBJECTIVES@#This study aims to describe the demographic profile and determine the proportion and Active Aging health determinants of staff, faculty, and retired employees who are 55 years of age and older.@*METHODS@#Mixed qualitative and quantitative methods, community-based, and participatory. Participants were working and retired faculty and staff, age 55 years and over, living within an urban campus of a University. The University Ethics Review Board approved the protocol. Focus group discussions (FGDs) led to the development of a pretested survey instrument. Additional health data were obtained using a validated Comprehensive Geriatric Assessment (CGA) tool. Trained and certified health professionals conducted the CGA. A Senior Geriatrician adjudicated the final diagnoses. Progress reports and validation workshops were conducted with study participants, content experts, and stakeholders. CSPRo, SPSS, and STATA were used to generate and analyze disaggregated data.@*RESULTS@#Two hundred thirty-one (n=231) agreed to participate. The matched dataset was used in data analysis, representing a total of n=192 completed both surveys and CGA interview. Of the top 10 Geriatrician diagnoses, the highest-ranking non-communicable disease was hypertension and the top sensory diagnosis was presbyopia. Three of the self-assessed conditions were vision-related. They had better oral health than the recent national report. Most were highly independent and functional. The majority rated their QOL as good. Most had access to health insurance and a University Health Service.@*CONCLUSION@#Non-communicable diseases and visual disorders were the most common medical problems among working and retired university workers 55 years and older, living within the campus. To reduce NCDs, maintain functional independence and achieve a better quality of life especially among the retired, programs for older persons are recommended. These include access to medication, improved health financing, and senior wellness programs during and after employment. The results of the study will help understand and create a Framework for Active Aging that is relevant to this academic community.

Post-Flood Impact on the Quality of Life of Victims in East Coast Malaysia

@#Introduction This study aimed to evaluate the quality of life among flood victims exposed at three worst districts in Pahang, Malaysia Methods Semi-guided questionnaires were distributed randomly to a total of 602 flood victims. Quality of life (QOL) was measured using WHO Quality of LifeBREF (WHOQOL-BREF), which was assessed based on four domains, i.e. physical activity, psychological, social relationships and environment. Results Victims of the flood had a poorer quality of life in all the domains especially physical (59.0%) and psychological (53.3%) domain. The impact of the flood on QOL was higher among women, those who reside in the urban area, the elderlies and persons with high education and income. Conclusions Flood event has reduced the QOL of victims. The impact of flood has been found to be mitigated over the time and relief efforts. Interventions aimed to reduce these concerns in acute post-flood areas are essential to minimize poor QOL among the affected victims.

Feature of “qi, Blood, Fluid” Factors in Patients with Sjögrenʼs Syndrome : In Comparison with Patients of Rheumatoid Arthritis in Remission / 日本東洋医学雑誌

To determine the body constituents patterns comprised of “qi, blood, fluid” factors associated with oral health-­related QOL (OHRQOL) of patients with Sjögren's syndrome (SS), 41 SS patients and 32 RA patients in remission were enrolled. The body constituents patterns were measured by using Terasawa's “qi, blood, fluid” score, and the simple version of yin deficiency questionnaire (yin-­deficiency score). OHRQOL were evaluated using the oral health impact profile (OHIP-­14). In the first study, the body constituents pattern scores were compared between SS group and RA (in remission) group, using the univariate and multivariate analysis. In the second study, the association between OHIP­14 and the body constituents pattern scores was analyzed. In the first study, all the scores were significantly higher in SS group, and the multivariable logistic regression identified yin deficiency (p = 0.02) and blood stasis (p = 0.01) as the significantly associated factors with SS group. In the second study, all the scores, except for the blood stasis pattern, showed positive correlation with OHIP-­14. The multiple regression analysis identified qi stagnation (p = 0.003) as the significantly associated factors with OHIP­-14. This study revealed that yin deficiency and blood stasis are the significant body constituent patterns in SS patients. In the low OHRQOL cases, qi stagnation should be taken into consideration.

Quality of life after gender reassignment surgery in transwomen

Background: Gender dysphoria is a condition in which there is discrepancy between a person's gender identity and that person's sex assigned at birth. Gender reassignment surgery (GRS) has an important role in alleviating the distress caused by gender dysphoria and it is medically necessary. The literature on quality of life (QoL) of transgenders post-GRS is limited in India.Methods: This is a prospective study on transgender women who volunteered to undergo male to female (MtF) GRS from March 2015 to August 2017. The demographic details and the surgical complications were registered. The Quality of life using the WHOQOL-BREF questionnaire was measured both before and a year after the surgery. The data were compared and presented.Results: A total of 62 GRS were performed during the study period. In that, 43 patients are literate (69.35%) and only 31.93% are employed in a socially respectable position. Our study shows significant improvement in physical, psychological and social health domains after the Surgery. Highest improvement was observed in the psychological health domain. There were no major complications observed in our study group.Conclusions: The surgical management improved the QOL in the first three domains of WHOQOL-BREF instrument namely physical health, psychological health and social relationship. Among these three domains, there is a significant improvement in psychological health. Hence, GRS has an important role in relieving the psychological distress caused by gender dysphoria and significantly improves the quality of life postoperatively.

A Cross-sectional Assessment of Quality of Life among Pharmacy Academics

Introduction: These days, living a good quality life has become a luxury rather than a necessity and investigating the quality of life (QoL) across teaching professionals seems to be beneficial. This study aimed to determine the association between demographic and socioeconomic variables and the QoL among pharmacy academics. Methods: Stratified random sampling was applied to collect data using a pre-validated and self-administered questionnaire the Duke Health Profile (DHP). Statistical Package for Social Science (SPSS) ver. 22.0 was used to analyze the descriptive and inferential data.Results: One hundred and fifty-five pharmacy academics were included in this study where majority 98 (63.2%) were males and 57 (36.8%) were females. The majority 74.2% weremarried and 68.4% were having more than 5 years of teaching experience. A total of 123 ofthe pharmacy academics were more than 35 years old which accounted for 79.4% of the respondents. Various determinants like age, residence, gender, administrative position, marital status, monthly income, and teaching experience are the main factors affecting QoL among pharmacy academics. Conclusion: From the present study it could be concluded that QoL among pharmacy academics was significantly influenced by numerous socio-economic and demographic determinants

Evaluation of differences in health-related quality of life in patients receiving conventional versus newer anti-epileptic drugs

Background: Epilepsy is associated with stigma and bad health-related quality of life (HR-QOL) due to this, and side effects of the drug therapy. Newer anti-epileptics are claimed to be better than the conventional. We evaluated this based on comparison of HR-QOL in patients taking the respective therapy.Methods: An observational, cross-sectional, single point study involved 127 consenting patients from Neurology OPD at V.S. General Hospital. Quality of life in epilepsy-10 (QOLIE-10) questionnaire was used to measure HR-QOL in patients. SPSS software and Graphpad prism were used to analyze the variables.Results: Patients of 20-30 age group were commonly affected (37.80%) with a male predominance (56.69%). 41.73% were unemployed. The difference in HR-QOL between patients and controls in all three domains (epilepsy effects, mental effects, role function domains) of QOLIE-10 was significant (p=0.0002), indicating better HR-QOL in controls. The worst HR-QOL scores were found in Epilepsy effects domain. Metabolic adverse effects (38.58%) were the common ADRs. Sodium valproate was the most effective in controlling seizures (last seizure episode: 15 months). HR-QOL correlation between patients receiving monotherapy and polytherapy was significant (p=0.026) with monotherapy rendering a better HR-QOL. Comparison of HR-QOL between patients taking the conventional and the newer drugs was not significant (p=0.1768).Conclusions: Our study nullifies the claims that newer drugs are better than the conventional since no such benefit was seen in HR-QOL as well as ADRs. Our findings ruled out the belief that cases of epilepsy are better controlled with polytherapy.

Reference Data, Characteristics and Related Factors of Quality of Life Assessed by a Questionnaire of Patient’s Behavior Survey in the General Population in Japan

To decide the policy to promote palliative care properly, a new questionnaire has been added to Patient’s behavior survey to assess Quality of Life (QOL) of inpatients and outpatients in Japan. The aim of this study was to survey QOL score of general population in Japan by using a questionnaire of patient’s behavior survey. A large nationwide postal survey was conducted from January through February 2013 in Japan. A total of 2400 subjects were selected randomly from among members of the general population who were 20 to 79 years of age and lived in Japan. A total of 978 (41.1%) questionnaires were analyzed, and reference data of QOL score weighted by the national standard value of sex-age group population were calculated. Correlation coefficients were calculated between QOL score and SF-8TM, Patient Health Questionnaire-9 (PHQ-9), Eastern Cooperative Oncology Group Performance Status (ECOG), Memorial Symptom Assessment Scale (MSAS) score. In addition, sociodemographic factors related to QOL score were evaluated. From the perspectives of public health and administrative policy, the results of this survey will provide important basic data to evaluate patient’s behavior survey broadly and continuously with the goal of establishing a palliative care system in Japan.